MCQ Principles of Inheritance and Variation for ISC Class 12 Biology

MCQ Principles of Inheritance and Variation for ISC Class 12 Biology. These MCQ  / Objective Type Questions is based on latest reduced syllabus according 2021-22 session on bifurcated pattern. Main motto of MCQ Type Question is cracking the next upcoming exam of council. Visit official website CISCE for detail information about ISC Board Class-12 Biology.

MCQ Type Question Principles of Inheritance and Variation  for ISC Class 12 Biology


Board ISC
Class  12th (XII)
Subject Biology
Principles of Inheritance and Variation
Syllabus  on bifurcated syllabus (after reduction)
Session 2021-22
Topic MCQ / Objective Type Question

ISC Class-12 Biology MCQ Principles of Inheritance and Variation

Question 1 : Person having genotype IA IB would show the blood group as AB. This is because of

(a) pleiotropy
(b) co-dominance
(c) segregation
(d) incomplete dominance.

Answer: (b) co-dominance

Question 2 : A cross between two tall plants resulted in offspring having few dwarf plants. What would be the genotypes of both the parents ?

(a) TT and Tt
(b) Tt and Tt
(c) TT and TT
(d) Tt and It

Answer: (b) Tt and Tt

Question 3 : The test cross is used to determine the

(a) genotype of the plant

(b) phenotype of the plant
(c) both (a) and (b)
(d) None of the above

Answer : (a) genotype of the plant

Question 4 : If a genetic disease is transferred from a phenotypically normal but carrier female to only some of the male progeny, the disease is

(a) autosomal dominant
(b) autosomal recessive
(c) sex-linked dominant
(d) sex-linked recessive.

Answer: (d) sex-linked recessive.

Question 5 : The crossing of F1 to homozygous recessive parent is called

(a) back cross

(b) test cross

(c) F1 cross

(d) all of these

Answer : (b) test cross

Question 6 : In a cross between a male and female, both heterozygous for sickle cell anaemia gene, what percentage of the progeny will be diseased?

(a) 25%

(b) 100%

(c) 50%

(d) 75%

Answer : (b) 100%

Question 7 : Which of the following will not result in variations among siblings ?

(a) Independent assortment of genes
(b) Crossing over
(c) Linkage
(d) Mutation
Answer: (c) Linkage

Question 8 :  Mendel’s Law of independent assortment holds good for genes situated on the

(a) non-homologous chromosomes
(b) homologous chromosomes
(c) extra nuclear genetic element
(d) same chromosome.

Answer: (b) homologous chromosomes

Question 9 :  In humans, the dominance relationship between the A and B alleles of the ABO blood group gene is an example of

(a) complete dominance

(b) incomplete dominance
(c) codominance
(d) epistasis

Answer: (c) codominance

Question 10 : The production of gametes by the parents, formation of zygotes, the F1 and F2 plants, can be understood from a diagram called:

(a) Punnett square

(b) Net square

(c) Bullet square

(d) Punch square

Answer: (a) Punnett square

Question 11: Experimental verification of the chromosomal theory of inheritance was done by:

(a) Sutton

(b) Boveri

(c) Morgan

(d) Mendel

Answer: (c) Morgan

Question 12: The colour based contrasting traits in seven contrasting pairs, studied by Mendel in pea plant were

(a) 1
(b) 2
(c) 3
(d) 4

Answer: (c) 3

Question 13. _________ pairs of contrasting traits were studied by Mendel in pea plant.

(a) 6
(b) 7
(c) 8
(d) 10

Answer: (b) 7

Question 14. Which of the following characters was not chosen by Mendel ?

(a) Pod shape
(b) Pod colour
(c) Location of flower
(d) Location of pod

Answer: (d) Location of pod

Question 15: Genes which code for a pair of contrasting traits are known as

(a) dominant genes
(b) alleles
(c) linked genes
(d) none of these

Answer: (b) alleles

Question 16: The distance between the genes is measured by

(a) angstrom

(b) map unit

(c) Dobson unit

(d) millimetre

Answer : (b) map unit

Question 17:  Linkage reduces the frequency of

(a) hybrids.

(b) all parental types.
(c) homozygous recessive parents.
(d) heterozygous recessive parents.

Answer: (a) hybrids.

Question 18: Select the correct match

(a) Phenylketonuria – Autosomal dominant trait

(b) Sickle cell anemia – Autosomal recessive trait chromosome – 11

(c) Thalassemia – X linked

(d) Haemophilia – Y linked

Answer: (b) Sickle cell anemia – Autosomal recessive trait chromosome – 11

Question 19: A recessive allele is expressed in

(a) heterozygous condition only
(b) homozygous condition only
(c) F3 generation
(d) both homozygous and heterozygous conditions.

Answer: (b) homozygous condition only

Question 20: Name the scientist who discovered the laws of Heredity.

(a) Gregor Mendel
(b) Newton
(c) Punnett
(d) None of the above

Answer: (a) Gregor Mendel

Question 21: Who introduced chromosomal theory of inheritance?

(a) Mendel
(b) Sutton
(c) Reginald
(d) Boyen

Answer: (b) Sutton

Question 22: Success of mendal is

(a) Selection of Pea plant
(b) Studied of free characters
(c) More Characters selection
(d) Pea is Bisexual

Answer: (a) Selection of Pea plant

Question 23: The characters which appear in the first filial generation are called

(a) recessive characters
(b) dominant characters
(c) holandric characters
(d) lethal characters

Answer: (b) dominant characters

Question 24: What will be the distribution of phenotypic features in the first filial generation after a cross between a homozygous female and a heterozygous male for a single locus ?

(a) 3 : 1
(b) 1 : 2 : 1
(c) 1 : 1
(d) None of these

Answer: (c) 1 : 1

Question 25:  Distance between the genes and percentage of recombination shows

(a) a direct relationship

(b) an inverse relationship
(c) a parallel relationship
(d) no relationship

Answer : (a) a direct relationship

Question 26:  HbA and HbS alleles of normal and sickle celled RBC are

(a) dominant-recessive alleles.

(b) polygenic alleles.
(c) codominant alleles.
(d) multiple alleles.

Answer: (c) codominant alleles.

Question 27:  How many true-breeding pea plant varieties did Mendel select as pairs, which were similar except in one character with contrasting traits?

(a) 2

(b) 14

(c) 6

(d) 4

Answer: (b) 14

Question 28:  The plant Mendel used to study inheritance of two genes is

(a) Apple
(b) Mango
(c) Garden pea
(d) Potato

Answer: (c) Garden pea

Question 29:  Mendel published his work on inheritance of characters in

(a) 1870
(b) 1900
(c) 1865
(d) 1845

Answer: (c) 1865

Question 30: A couple has six daughters. What is the possibility of their having a girl next time ?

(a) 10 %
(b) 50 %
(c) 90 %
(d) 100 %

Answer: (b) 50 %

Question 31: Number of autosomes present in liver cells of a human female is

(a) 22 autosomes
(b) 22 pairs
(c) 23 autosomes
(d) 23 pairs

Answer: (b) 22 pairs

Question 32: Haplodiploidy is found in

(a) grasshoppers and cockroaches
(b) birds and reptiles
(c) butterflies and moths
(d) honeybees, ants and wasp.

Answer: (d) honeybees, ants and wasp.

Question 33: Sex is determined in human beings

(a) by ovum.

(b) at time of fertilization.
(c) 40 days after fertilization.
(d) seventh to eight week when genitals differentiate in foetus.

Answer: (b) at time of fertilization.

Question 34: Female heterogametic is

(a) two different types of gametes are produced by females.
(b) four different types of gametes are produced – by males.
(c) Can be both (a) and (b)
(d) None of the above

Answer: (a) two different types of gametes are produced by females.

Question 35: Haemophilia is a

(a) Mendalian disorder
(b) Chromosomal disorder
(c) Can be (a) or (b)
(d) None of the above

Answer: (a) Mendalian disorder

Question 36: Mendal formulated the law of purity of gametes on the basis of

(a) monohybrid cross
(b) dihybrid cross
(c) test cross
(d) back cross.

Answer: (a) monohybrid cross

Question 37: The inheritance of flower colour in Antirrhinum (dog flower) is an example of

(a) incomplete dominance
(b) co-dominance
(c) multiple alleles
(d) linkage.

Answer: (a) incomplete dominance

Question 38: ABO blood grouping in human beings cites the example of

(a) incomplete dominance
(b) co-dominance
(c) multiple allelism
(d) both
(b) and (c)

Answer: (b) and (c)

Question 39: In mice, Y is the dominant allele for yellow fur an y is the recessive allele for grey fur. Since Y is lethal when homozygous, the result of cross Yy × Yy will be

(a) 3 yellow : 1 grey
(b) 2 yellow : 1 grey
(c) 1 yellow : 1 grey
(d) 1 yellow : 2 grey

Answer: (b) 2 yellow : 1 grey

Question 40: The ‘X’ body of Henking was observed in

(a) all sperms during spermatogenesis.
(b) all eggs during oogenesis.
(c) half of the sperms during spermatogenesis.
(d) half of the eggs during oogenesis.

Answer: (c) half of the sperms during spermatogenesis.

Question 41: Down’s syndrome is a

(a) Mendelian disorder
(b) Chromosomal disorder
(c) Can be (a) or (b)
(d) None of the above

Answer: (b) Chromosomal disorder

Question 42: An analysis of traits in several generation of a family is called the

(a) Pedigree analysis
(b) Mendel analysis
(c) Punneet analysis
(d) None of the above

Answer: (a) Pedigree analysis

Question 43: How many types of gametes can be produced by a diploid organism who is heterozygous for 4 loci ?

(a) 4
(b) 8
(c) 16
(d) 32

Answer: (c) 16

Question 44: Which of the following is correct for the condition when plant YyRr is back crossed with the double recessive parent ?

(a) 9 : 3 : 3 : 1 ratio of phenotypes only
(b) 9 : 3 : 3 : 1 ratio of genotypes only
(c) 1 : 1 : 1 : 1 ratio of phenotypes only
(d) 1 : 1 : 1 : 1 ratio of phenotypes and genotypes

Answer: (d) 1 : 1 : 1 : 1 ratio of phenotypes and genotypes

Question 45: Law of independent assortment can be explained with the help of

(a) dihybrid
(b) test cross
(c) back cross
(d) monohybrid cross

Answer: (a) dihybrid

Question 46:  The number of contrasting characters studied by Mendel for his experiments was :

(a) 14

(b) 4

(c) 2

(d) 7

Answer: (d) 7

Question 47: Failure of segregation of chomatids during cell division cycle results in the gain or loss of a chromosome(s) is called

(a) Female heterogamety
(b) Male heterogamety
(c) Aneuploidy
(d) None of the above

Answer: (c) Aneuploidy

Question 48: Mendel’s work was rediscovered by three scientists in the year

(a) 1865
(b) 1900
(c) 1910
(d) 1920

Answer: (b) 1900

Question 49: Which three scientists independently rediscovered Mendel’s work ?

(a) Avery, McLeod, McCarty
(b) Sutton, Morgan and Bridges
(c) Bateson, Punnet and Bridges
(d) de Vries, Correns and Tschemark

Answer: (d) de Vries, Correns and Tschemark

Question 50: Experimental verification of ‘chromosomal theory of inheritance’ was done by

(a) Sutton and Boveri
(b) Morgan et al
(c) Henking
(d) Karl Correns.

Answer: (b) Morgan et al

Question 51 : Genes located very close to one another on same chromosome tend to be transmitted together and are called as

(a) allelomorphs
(b) identical genes
(c) linked genes
(d) recessive genes

Answer: (c) linked genes

Question 52: Punnett square was developed by

(a) Mendel
(b) Watson and Sútton
(c) Reginald
(d) Correns

Answer: (c) Reginald

Question 53: Two genes very close on a chromosome will show:

(a) No crossing over
(b) High crossing over
(c) Hardly an crossing over
(d) Only double crossing overy

Answer: (a) No crossing over

Question 54:  An lndividual with into identical alleles is:

(a) Hybrid
(b) Dominant
(c) Homozygous
(d) Heterozygous

Answer: (c) Homozygous

Question 55:  If linkage was known at the time of Mendel then which of the following laws, he would not have been able to explain ?

(a) Law of dominance
(b) Law of independent assortment
(c) Law of segregation
(d) Law of purity of gametes

Answer: (b) Law of independent assortment

-: End of MCQ Principles of Inheritance and Variation for ISC Class 12 Biology :-

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